Chromatin Immunoprecipitation Assay

The likelihood of success with the Chromatin Immunoprecipitation Assay / ChIP method is protein and antibody dependent, but the methods track record suggests that this technique is extremely versatile and widely applicable. Success will depend on the abundance of the desired protein-DNA adducts being studied, the quality and affinity of the antibodies being used, and on the size and complexity of the genetic loci studied.